Cytoplasmic vesicle, secretory vesicle membrane. ZnT8A predicted diabetes independently of ICA, the standard BAA, age, and HLA type. Human Zinc transporter 8(SLC30A8) ELISA kit Subcellular Location, Cell membrane Multi-pass membrane protein. People with LADA often show highly varying beta cell destruction, different degrees of insulin resistance and different titre levels of autoantibodies. Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies In relatives with one standard BAA, ZnT8A identified a subset at higher diabetes risk. People with adult-onset autoimmune diabetes who do not need insulin for at least 6 months after diagnosis are deemed as having LADA (latent autoimmune diabetes in adults). Type 1 and LADA diabetes are both an autoimmune disease. This is certainly appears paradoxal as you indicate having 2 very high levels of auto antibodies, GADA (578 and ZNT8 (500 u/mL) which almost always points to a very high risk for development of type 1 diabetes yet your insulin secretion is within reference range and your not on any insulin and taking just metformin and glypizide with an a1c of 6.0.Īs for LADA, in a high majority of cases, GADA is elevated whereby ZNT8 and IA-2 are within normal range and can take 6 months to 5 years to require daily insulin. do you have any previous c-peptide tests to measure against? So my doctor put me back on metaformin and after taking metaformin for about another 2 months I didn’t see no difference in my blood sugar levels they were still 200-350+ so my doctor put me on glipizide and metaformin and after taking those for another 2 months I didn’t see no difference in myblood sugar levels, so I bought a treadmill and started running twice a day for about 3 months And saw a huge difference in my blood sugar levels I was waking up with 120-150 blood sugars everyday and I went back to take aA1c test In September 2020 and my A1c was 6.0, so the only way my A1c went down was by running twice a day ,And I’m currently taking glipizide and metaformin and now they seem to be working to lower my blood sugar but I recently got tested for GAD ANTIBODIES AND ZNT8 antibodies and they both came back 500+ positive, im very confused about my diagnosis, I’m going to see a diabetes specialist soon.įasting c-peptide of 1.1 in the normal range. ![]() I’m very confused with my diabetes diagnoses, i was diagnosed with type 2 diabetes around July 2019 with a A1c of 7.0 and was put on metaformin and quickly I brought it down to 5.6 A1c in about 3 months from my diagnosis and my doctor took me off metaformin to see if I can control my diabetes without metaformin with just diet and exercise and about 3 months after being off metaformin my A1c was 8.7 and my blood sugar levels were constantly 200-350+all day
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |